Regulation of Glucose Production in Newborn Infants of Diabetic Mothers

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Glucose regulation in preterm newborn infants.

After birth, continuous transplacental transfer of glucose is interrupted. Neonates have to provide brain and vital organs with sufficient glucose. In term newborn infants, this is accomplished through well-coordinated hormonal and metabolic adaptive changes. During the first week of life, preterm infants are at high risk of abnormal glucose homeostasis. They are at risk of hypoglycemia due to ...

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The development of glucose metabolism in infants of diabetic mothers.

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9 Grodsky, G. M., and Forsham, P. H.: An immunochemical assay of total extractable insulin in man. J. Clin. Invest. 39:1070, i960. 10 Field, J. B., and Woodson, M. L.: Studies on the circulating insulin inhibitor found in some diabetic patients exhibiting chronic insulin resistance. J. Clin. Invest. 38:551, 1959. 11 Mitchell, M. L.: Interaction of radioinsulin with serum proteins in vitro and w...

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Advances in the management of the mother with diabetes have reduced the rate of morbidity and mortality for her infant. Aggressive control of maternal glycemic status is warranted, because most morbidities are epidemiologically and pathophysiologically closely linked to fetal hyperglycemia and hyperinsulinemia. The burgeoning public health problem of overweight and obesity in children will like...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1982

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-198208000-00005